Methoxyflurane
Methoxyflurane Brand names, Methoxyflurane Analogs
Methoxyflurane Brand Names Mixture
- No information avaliable
Methoxyflurane Chemical_Formula
C3H4Cl2F2O
Methoxyflurane RX_link
No information avaliable
Methoxyflurane fda sheet
Methoxyflurane msds (material safety sheet)
Methoxyflurane Synthesis Reference
Miller et al., J. Am. Chem. Soc. 70, 431 (1948)
Methoxyflurane Molecular Weight
164.965 g/mol
Methoxyflurane Melting Point
-35 oC (melting point), 105 oC (boiling point)
Methoxyflurane H2O Solubility
2.83E+004 mg/L
Methoxyflurane State
Liquid
Methoxyflurane LogP
2.073
Methoxyflurane Dosage Forms
Spray
Methoxyflurane Indication
For use in the induction and maintenance of general anesthesia
Methoxyflurane Pharmacology
Methoxyflurane is a general inhalation anesthetic used for induction and maintenance of general anesthesia. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential.
Methoxyflurane Absorption
No information avaliable
Methoxyflurane side effects and Toxicity
LD50=3600 mg/kg (Orally in rats). Symptoms of overexposure include eye irritation, CNS depression, analgesia, anesthesia, seizures, respiratory depression, and liver and kidney damage.
Methoxyflurane Patient Information
No information avaliable
Methoxyflurane Organisms Affected
Humans and other mammals
