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Metofane Brand names, Metofane Analogs

Metofane Brand Names Mixture

  • No information avaliable

Metofane Chemical_Formula

C3H4Cl2F2O

Metofane RX_link

No information avaliable

Metofane fda sheet

Metofane msds (material safety sheet)

Metofane MSDS

Metofane Synthesis Reference

Miller et al., J. Am. Chem. Soc. 70, 431 (1948)

Metofane Molecular Weight

164.965 g/mol

Metofane Melting Point

-35 oC (melting point), 105 oC (boiling point)

Metofane H2O Solubility

2.83E+004 mg/L

Metofane State

Liquid

Metofane LogP

2.073

Metofane Dosage Forms

Spray

Metofane Indication

For use in the induction and maintenance of general anesthesia

Metofane Pharmacology

Methoxyflurane is a general inhalation anesthetic used for induction and maintenance of general anesthesia. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential.

Metofane Absorption

No information avaliable

Metofane side effects and Toxicity

LD50=3600 mg/kg (Orally in rats). Symptoms of overexposure include eye irritation, CNS depression, analgesia, anesthesia, seizures, respiratory depression, and liver and kidney damage.

Metofane Patient Information

No information avaliable

Metofane Organisms Affected

Humans and other mammals