Metofane
Metofane Brand names, Metofane Analogs
Metofane Brand Names Mixture
- No information avaliable
Metofane Chemical_Formula
C3H4Cl2F2O
Metofane RX_link
No information avaliable
Metofane fda sheet
Metofane msds (material safety sheet)
Metofane Synthesis Reference
Miller et al., J. Am. Chem. Soc. 70, 431 (1948)
Metofane Molecular Weight
164.965 g/mol
Metofane Melting Point
-35 oC (melting point), 105 oC (boiling point)
Metofane H2O Solubility
2.83E+004 mg/L
Metofane State
Liquid
Metofane LogP
2.073
Metofane Dosage Forms
Spray
Metofane Indication
For use in the induction and maintenance of general anesthesia
Metofane Pharmacology
Methoxyflurane is a general inhalation anesthetic used for induction and maintenance of general anesthesia. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential.
Metofane Absorption
No information avaliable
Metofane side effects and Toxicity
LD50=3600 mg/kg (Orally in rats). Symptoms of overexposure include eye irritation, CNS depression, analgesia, anesthesia, seizures, respiratory depression, and liver and kidney damage.
Metofane Patient Information
No information avaliable
Metofane Organisms Affected
Humans and other mammals
