Methoflurane
Methoflurane Brand names, Methoflurane Analogs
Methoflurane Brand Names Mixture
- No information avaliable
Methoflurane Chemical_Formula
C3H4Cl2F2O
Methoflurane RX_link
No information avaliable
Methoflurane fda sheet
Methoflurane msds (material safety sheet)
Methoflurane Synthesis Reference
Miller et al., J. Am. Chem. Soc. 70, 431 (1948)
Methoflurane Molecular Weight
164.965 g/mol
Methoflurane Melting Point
-35 oC (melting point), 105 oC (boiling point)
Methoflurane H2O Solubility
2.83E+004 mg/L
Methoflurane State
Liquid
Methoflurane LogP
2.073
Methoflurane Dosage Forms
Spray
Methoflurane Indication
For use in the induction and maintenance of general anesthesia
Methoflurane Pharmacology
Methoxyflurane is a general inhalation anesthetic used for induction and maintenance of general anesthesia. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential.
Methoflurane Absorption
No information avaliable
Methoflurane side effects and Toxicity
LD50=3600 mg/kg (Orally in rats). Symptoms of overexposure include eye irritation, CNS depression, analgesia, anesthesia, seizures, respiratory depression, and liver and kidney damage.
Methoflurane Patient Information
No information avaliable
Methoflurane Organisms Affected
Humans and other mammals
