Methoxane
Brand names,
Methoxane
Analogs
Methoxane
Brand Names Mixture
Methoxane
Chemical_Formula
C3H4Cl2F2O
Methoxane
RX_link
No information avaliable
Methoxane
fda sheet
Methoxane
msds (material safety sheet)
Methoxane
Synthesis Reference
Miller et al., J. Am. Chem. Soc. 70, 431 (1948)
Methoxane
Molecular Weight
164.965 g/mol
Methoxane
Melting Point
-35 oC (melting point), 105 oC (boiling point)
Methoxane
H2O Solubility
2.83E+004 mg/L
Methoxane
State
Liquid
Methoxane
LogP
2.073
Methoxane
Dosage Forms
Spray
Methoxane
Indication
For use in the induction and maintenance of general anesthesia
Methoxane
Pharmacology
Methoxyflurane is a general inhalation anesthetic used for induction and maintenance of general anesthesia. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential.
Methoxane
Absorption
No information avaliable
Methoxane
side effects and Toxicity
LD50=3600 mg/kg (Orally in rats). Symptoms of overexposure include eye irritation, CNS depression, analgesia, anesthesia, seizures, respiratory depression, and liver and kidney damage.
Methoxane
Patient Information
No information avaliable
Methoxane
Organisms Affected
Humans and other mammals