Pentrane
Brand names,
Pentrane
Analogs
Pentrane
Brand Names Mixture
Pentrane
Chemical_Formula
C3H4Cl2F2O
Pentrane
RX_link
No information avaliable
Pentrane
fda sheet
Pentrane
msds (material safety sheet)
Pentrane
Synthesis Reference
Miller et al., J. Am. Chem. Soc. 70, 431 (1948)
Pentrane
Molecular Weight
164.965 g/mol
Pentrane
Melting Point
-35 oC (melting point), 105 oC (boiling point)
Pentrane
H2O Solubility
2.83E+004 mg/L
Pentrane
State
Liquid
Pentrane
LogP
2.073
Pentrane
Dosage Forms
Spray
Pentrane
Indication
For use in the induction and maintenance of general anesthesia
Pentrane
Pharmacology
Methoxyflurane is a general inhalation anesthetic used for induction and maintenance of general anesthesia. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential.
Pentrane
Absorption
No information avaliable
Pentrane
side effects and Toxicity
LD50=3600 mg/kg (Orally in rats). Symptoms of overexposure include eye irritation, CNS depression, analgesia, anesthesia, seizures, respiratory depression, and liver and kidney damage.
Pentrane
Patient Information
No information avaliable
Pentrane
Organisms Affected
Humans and other mammals