Methoxifluranum
Methoxifluranum Brand names, Methoxifluranum Analogs
Methoxifluranum Brand Names Mixture
- No information avaliable
Methoxifluranum Chemical_Formula
C3H4Cl2F2O
Methoxifluranum RX_link
No information avaliable
Methoxifluranum fda sheet
Methoxifluranum msds (material safety sheet)
Methoxifluranum Synthesis Reference
Miller et al., J. Am. Chem. Soc. 70, 431 (1948)
Methoxifluranum Molecular Weight
164.965 g/mol
Methoxifluranum Melting Point
-35 oC (melting point), 105 oC (boiling point)
Methoxifluranum H2O Solubility
2.83E+004 mg/L
Methoxifluranum State
Liquid
Methoxifluranum LogP
2.073
Methoxifluranum Dosage Forms
Spray
Methoxifluranum Indication
For use in the induction and maintenance of general anesthesia
Methoxifluranum Pharmacology
Methoxyflurane is a general inhalation anesthetic used for induction and maintenance of general anesthesia. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential.
Methoxifluranum Absorption
No information avaliable
Methoxifluranum side effects and Toxicity
LD50=3600 mg/kg (Orally in rats). Symptoms of overexposure include eye irritation, CNS depression, analgesia, anesthesia, seizures, respiratory depression, and liver and kidney damage.
Methoxifluranum Patient Information
No information avaliable
Methoxifluranum Organisms Affected
Humans and other mammals
