Inhalan
Brand names,
Inhalan
Analogs
Inhalan
Brand Names Mixture
Inhalan
Chemical_Formula
C3H4Cl2F2O
Inhalan
RX_link
No information avaliable
Inhalan
fda sheet
Inhalan
msds (material safety sheet)
Inhalan
Synthesis Reference
Miller et al., J. Am. Chem. Soc. 70, 431 (1948)
Inhalan
Molecular Weight
164.965 g/mol
Inhalan
Melting Point
-35 oC (melting point), 105 oC (boiling point)
Inhalan
H2O Solubility
2.83E+004 mg/L
Inhalan
State
Liquid
Inhalan
LogP
2.073
Inhalan
Dosage Forms
Spray
Inhalan
Indication
For use in the induction and maintenance of general anesthesia
Inhalan
Pharmacology
Methoxyflurane is a general inhalation anesthetic used for induction and maintenance of general anesthesia. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential.
Inhalan
Absorption
No information avaliable
Inhalan
side effects and Toxicity
LD50=3600 mg/kg (Orally in rats). Symptoms of overexposure include eye irritation, CNS depression, analgesia, anesthesia, seizures, respiratory depression, and liver and kidney damage.
Inhalan
Patient Information
No information avaliable
Inhalan
Organisms Affected
Humans and other mammals