Analgizer
Brand names,
Analgizer
Analogs
Analgizer
Brand Names Mixture
Analgizer
Chemical_Formula
C3H4Cl2F2O
Analgizer
RX_link
No information avaliable
Analgizer
fda sheet
Analgizer
msds (material safety sheet)
Analgizer
Synthesis Reference
Miller et al., J. Am. Chem. Soc. 70, 431 (1948)
Analgizer
Molecular Weight
164.965 g/mol
Analgizer
Melting Point
-35 oC (melting point), 105 oC (boiling point)
Analgizer
H2O Solubility
2.83E+004 mg/L
Analgizer
State
Liquid
Analgizer
LogP
2.073
Analgizer
Dosage Forms
Spray
Analgizer
Indication
For use in the induction and maintenance of general anesthesia
Analgizer
Pharmacology
Methoxyflurane is a general inhalation anesthetic used for induction and maintenance of general anesthesia. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential.
Analgizer
Absorption
No information avaliable
Analgizer
side effects and Toxicity
LD50=3600 mg/kg (Orally in rats). Symptoms of overexposure include eye irritation, CNS depression, analgesia, anesthesia, seizures, respiratory depression, and liver and kidney damage.
Analgizer
Patient Information
No information avaliable
Analgizer
Organisms Affected
Humans and other mammals