Pentran
Brand names,
Pentran
Analogs
Pentran
Brand Names Mixture
Pentran
Chemical_Formula
C3H4Cl2F2O
Pentran
RX_link
No information avaliable
Pentran
fda sheet
Pentran
msds (material safety sheet)
Pentran
Synthesis Reference
Miller et al., J. Am. Chem. Soc. 70, 431 (1948)
Pentran
Molecular Weight
164.965 g/mol
Pentran
Melting Point
-35 oC (melting point), 105 oC (boiling point)
Pentran
H2O Solubility
2.83E+004 mg/L
Pentran
State
Liquid
Pentran
LogP
2.073
Pentran
Dosage Forms
Spray
Pentran
Indication
For use in the induction and maintenance of general anesthesia
Pentran
Pharmacology
Methoxyflurane is a general inhalation anesthetic used for induction and maintenance of general anesthesia. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential.
Pentran
Absorption
No information avaliable
Pentran
side effects and Toxicity
LD50=3600 mg/kg (Orally in rats). Symptoms of overexposure include eye irritation, CNS depression, analgesia, anesthesia, seizures, respiratory depression, and liver and kidney damage.
Pentran
Patient Information
No information avaliable
Pentran
Organisms Affected
Humans and other mammals