Metossiflurano [Dcit]
Metossiflurano [Dcit] Brand names, Metossiflurano [Dcit] Analogs
Metossiflurano [Dcit] Brand Names Mixture
- No information avaliable
Metossiflurano [Dcit] Chemical_Formula
C3H4Cl2F2O
Metossiflurano [Dcit] RX_link
No information avaliable
Metossiflurano [Dcit] fda sheet
Metossiflurano [Dcit] msds (material safety sheet)
Metossiflurano [Dcit] Synthesis Reference
Miller et al., J. Am. Chem. Soc. 70, 431 (1948)
Metossiflurano [Dcit] Molecular Weight
164.965 g/mol
Metossiflurano [Dcit] Melting Point
-35 oC (melting point), 105 oC (boiling point)
Metossiflurano [Dcit] H2O Solubility
2.83E+004 mg/L
Metossiflurano [Dcit] State
Liquid
Metossiflurano [Dcit] LogP
2.073
Metossiflurano [Dcit] Dosage Forms
Spray
Metossiflurano [Dcit] Indication
For use in the induction and maintenance of general anesthesia
Metossiflurano [Dcit] Pharmacology
Methoxyflurane is a general inhalation anesthetic used for induction and maintenance of general anesthesia. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential.
Metossiflurano [Dcit] Absorption
No information avaliable
Metossiflurano [Dcit] side effects and Toxicity
LD50=3600 mg/kg (Orally in rats). Symptoms of overexposure include eye irritation, CNS depression, analgesia, anesthesia, seizures, respiratory depression, and liver and kidney damage.
Metossiflurano [Dcit] Patient Information
No information avaliable
Metossiflurano [Dcit] Organisms Affected
Humans and other mammals
![Metossiflurano_[Dcit]](/images/rx/APRD00744.gif)
