Methoxiflurane
Methoxiflurane Brand names, Methoxiflurane Analogs
Methoxiflurane Brand Names Mixture
- No information avaliable
Methoxiflurane Chemical_Formula
C3H4Cl2F2O
Methoxiflurane RX_link
No information avaliable
Methoxiflurane fda sheet
Methoxiflurane msds (material safety sheet)
Methoxiflurane Synthesis Reference
Miller et al., J. Am. Chem. Soc. 70, 431 (1948)
Methoxiflurane Molecular Weight
164.965 g/mol
Methoxiflurane Melting Point
-35 oC (melting point), 105 oC (boiling point)
Methoxiflurane H2O Solubility
2.83E+004 mg/L
Methoxiflurane State
Liquid
Methoxiflurane LogP
2.073
Methoxiflurane Dosage Forms
Spray
Methoxiflurane Indication
For use in the induction and maintenance of general anesthesia
Methoxiflurane Pharmacology
Methoxyflurane is a general inhalation anesthetic used for induction and maintenance of general anesthesia. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential.
Methoxiflurane Absorption
No information avaliable
Methoxiflurane side effects and Toxicity
LD50=3600 mg/kg (Orally in rats). Symptoms of overexposure include eye irritation, CNS depression, analgesia, anesthesia, seizures, respiratory depression, and liver and kidney damage.
Methoxiflurane Patient Information
No information avaliable
Methoxiflurane Organisms Affected
Humans and other mammals
