Metoxifluran
Metoxifluran Brand names, Metoxifluran Analogs
Metoxifluran Brand Names Mixture
- No information avaliable
Metoxifluran Chemical_Formula
C3H4Cl2F2O
Metoxifluran RX_link
No information avaliable
Metoxifluran fda sheet
Metoxifluran msds (material safety sheet)
Metoxifluran Synthesis Reference
Miller et al., J. Am. Chem. Soc. 70, 431 (1948)
Metoxifluran Molecular Weight
164.965 g/mol
Metoxifluran Melting Point
-35 oC (melting point), 105 oC (boiling point)
Metoxifluran H2O Solubility
2.83E+004 mg/L
Metoxifluran State
Liquid
Metoxifluran LogP
2.073
Metoxifluran Dosage Forms
Spray
Metoxifluran Indication
For use in the induction and maintenance of general anesthesia
Metoxifluran Pharmacology
Methoxyflurane is a general inhalation anesthetic used for induction and maintenance of general anesthesia. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential.
Metoxifluran Absorption
No information avaliable
Metoxifluran side effects and Toxicity
LD50=3600 mg/kg (Orally in rats). Symptoms of overexposure include eye irritation, CNS depression, analgesia, anesthesia, seizures, respiratory depression, and liver and kidney damage.
Metoxifluran Patient Information
No information avaliable
Metoxifluran Organisms Affected
Humans and other mammals
