Methoxyfluoran
Brand names,
Methoxyfluoran
Analogs
Methoxyfluoran
Brand Names Mixture
Methoxyfluoran
Chemical_Formula
C3H4Cl2F2O
Methoxyfluoran
RX_link
No information avaliable
Methoxyfluoran
fda sheet
Methoxyfluoran
msds (material safety sheet)
Methoxyfluoran
Synthesis Reference
Miller et al., J. Am. Chem. Soc. 70, 431 (1948)
Methoxyfluoran
Molecular Weight
164.965 g/mol
Methoxyfluoran
Melting Point
-35 oC (melting point), 105 oC (boiling point)
Methoxyfluoran
H2O Solubility
2.83E+004 mg/L
Methoxyfluoran
State
Liquid
Methoxyfluoran
LogP
2.073
Methoxyfluoran
Dosage Forms
Spray
Methoxyfluoran
Indication
For use in the induction and maintenance of general anesthesia
Methoxyfluoran
Pharmacology
Methoxyflurane is a general inhalation anesthetic used for induction and maintenance of general anesthesia. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential.
Methoxyfluoran
Absorption
No information avaliable
Methoxyfluoran
side effects and Toxicity
LD50=3600 mg/kg (Orally in rats). Symptoms of overexposure include eye irritation, CNS depression, analgesia, anesthesia, seizures, respiratory depression, and liver and kidney damage.
Methoxyfluoran
Patient Information
No information avaliable
Methoxyfluoran
Organisms Affected
Humans and other mammals