Ibenzmethyzine hydrochloride en es it fr

Ibenzmethyzine hydrochloride Brand names, Ibenzmethyzine hydrochloride Analogs

Ibenzmethyzine hydrochloride Brand Names Mixture

  • No information avaliable

Ibenzmethyzine hydrochloride Chemical_Formula

C12H19N3O

Ibenzmethyzine hydrochloride RX_link

http://www.rxlist.com/cgi/generic3/procarb.htm

Ibenzmethyzine hydrochloride fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=44

Ibenzmethyzine hydrochloride msds (material safety sheet)

Ibenzmethyzine_hydrochloride MSDS

Ibenzmethyzine hydrochloride Synthesis Reference

No information avaliable

Ibenzmethyzine hydrochloride Molecular Weight

221.299 g/mol

Ibenzmethyzine hydrochloride Melting Point

223 oC

Ibenzmethyzine hydrochloride H2O Solubility

1420 mg/L

Ibenzmethyzine hydrochloride State

Solid

Ibenzmethyzine hydrochloride LogP

1.234

Ibenzmethyzine hydrochloride Dosage Forms

Capsule

Ibenzmethyzine hydrochloride Indication

For use with other anticancer drugs for the treatment of stage III and stage IV Hodgkin's disease.

Ibenzmethyzine hydrochloride Pharmacology

Procarbazine is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Procarbazine is cell-phase specific for the S phase of cell division.

Ibenzmethyzine hydrochloride Absorption

Procarbazine is rapidly and completely absorbed.

Ibenzmethyzine hydrochloride side effects and Toxicity

LD50=785 mg/kg (orally in rats)

Ibenzmethyzine hydrochloride Patient Information

Ibenzmethyzine hydrochloride Organisms Affected

Humans and other mammals