PharmacyCodes



Buclizine en es it fr

Buclizine Brand names, Buclizine Analogs

Buclizine Brand Names Mixture

  • No information avaliable

Buclizine Chemical_Formula

C28H33ClN2

Buclizine RX_link

No information avaliable

Buclizine fda sheet

Buclizine msds (material safety sheet)

Buclizine Synthesis Reference

No information avaliable

Buclizine Molecular Weight

433.028 g/mol

Buclizine Melting Point

218 oC (BP)

Buclizine H2O Solubility

No information avaliable

Buclizine State

Liquid

Buclizine LogP

7.749

Buclizine Dosage Forms

Tablet (50 mg)

Buclizine Indication

For prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness and vertigo (dizziness caused by other medical problems).

Buclizine Pharmacology

Buclizine is a piperazine-derivative antihistamine used as an antivertigo/antiemetic agent. Buclizine is used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus. Although the mechanism by which buclizine exerts its antiemetic and antivertigo effects has not been fully elucidated, its central anticholinergic properties are partially responsible. The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone. It also possesses anticholinergic, antihistaminic, central nervous system depressant, and local anesthetic effects.

Buclizine Absorption

Rapidly absorbed following oral administration.

Buclizine side effects and Toxicity

No information avaliable

Buclizine Patient Information

Buclizine Organisms Affected

Humans and other mammals