Vibazine Hydrochloride
Brand names,
Vibazine Hydrochloride
Analogs
Vibazine Hydrochloride
Brand Names Mixture
Vibazine Hydrochloride
Chemical_Formula
C28H33ClN2
Vibazine Hydrochloride
RX_link
No information avaliable
Vibazine Hydrochloride
fda sheet
Vibazine Hydrochloride
msds (material safety sheet)
Vibazine Hydrochloride
Synthesis Reference
No information avaliable
Vibazine Hydrochloride
Molecular Weight
433.028 g/mol
Vibazine Hydrochloride
Melting Point
218 oC (BP)
Vibazine Hydrochloride
H2O Solubility
No information avaliable
Vibazine Hydrochloride
State
Liquid
Vibazine Hydrochloride
LogP
7.749
Vibazine Hydrochloride
Dosage Forms
Tablet (50 mg)
Vibazine Hydrochloride
Indication
For prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness and vertigo (dizziness caused by other medical problems).
Vibazine Hydrochloride
Pharmacology
Buclizine is a piperazine-derivative antihistamine used as an antivertigo/antiemetic agent. Buclizine is used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus. Although the mechanism by which buclizine exerts its antiemetic and antivertigo effects has not been fully elucidated, its central anticholinergic properties are partially responsible. The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone. It also possesses anticholinergic, antihistaminic, central nervous system depressant, and local anesthetic effects.
Vibazine Hydrochloride
Absorption
Rapidly absorbed following oral administration.
Vibazine Hydrochloride
side effects and Toxicity
No information avaliable
Vibazine Hydrochloride
Patient Information
Vibazine Hydrochloride
Organisms Affected
Humans and other mammals