PharmacyCodes



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Buclifen Brand names, Buclifen Analogs

Buclifen Brand Names Mixture

  • No information avaliable

Buclifen Chemical_Formula

C28H33ClN2

Buclifen RX_link

No information avaliable

Buclifen fda sheet

Buclifen msds (material safety sheet)

Buclifen Synthesis Reference

No information avaliable

Buclifen Molecular Weight

433.028 g/mol

Buclifen Melting Point

218 oC (BP)

Buclifen H2O Solubility

No information avaliable

Buclifen State

Liquid

Buclifen LogP

7.749

Buclifen Dosage Forms

Tablet (50 mg)

Buclifen Indication

For prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness and vertigo (dizziness caused by other medical problems).

Buclifen Pharmacology

Buclizine is a piperazine-derivative antihistamine used as an antivertigo/antiemetic agent. Buclizine is used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus. Although the mechanism by which buclizine exerts its antiemetic and antivertigo effects has not been fully elucidated, its central anticholinergic properties are partially responsible. The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone. It also possesses anticholinergic, antihistaminic, central nervous system depressant, and local anesthetic effects.

Buclifen Absorption

Rapidly absorbed following oral administration.

Buclifen side effects and Toxicity

No information avaliable

Buclifen Patient Information

Buclifen Organisms Affected

Humans and other mammals