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Bucladin Brand names, Bucladin Analogs

Bucladin Brand Names Mixture

  • No information avaliable

Bucladin Chemical_Formula

C28H33ClN2

Bucladin RX_link

No information avaliable

Bucladin fda sheet

Bucladin msds (material safety sheet)

Bucladin Synthesis Reference

No information avaliable

Bucladin Molecular Weight

433.028 g/mol

Bucladin Melting Point

218 oC (BP)

Bucladin H2O Solubility

No information avaliable

Bucladin State

Liquid

Bucladin LogP

7.749

Bucladin Dosage Forms

Tablet (50 mg)

Bucladin Indication

For prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness and vertigo (dizziness caused by other medical problems).

Bucladin Pharmacology

Buclizine is a piperazine-derivative antihistamine used as an antivertigo/antiemetic agent. Buclizine is used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus. Although the mechanism by which buclizine exerts its antiemetic and antivertigo effects has not been fully elucidated, its central anticholinergic properties are partially responsible. The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone. It also possesses anticholinergic, antihistaminic, central nervous system depressant, and local anesthetic effects.

Bucladin Absorption

Rapidly absorbed following oral administration.

Bucladin side effects and Toxicity

No information avaliable

Bucladin Patient Information

Bucladin Organisms Affected

Humans and other mammals