Histabutyzine Hydrochloride
Brand names,
Histabutyzine Hydrochloride
Analogs
Histabutyzine Hydrochloride
Brand Names Mixture
Histabutyzine Hydrochloride
Chemical_Formula
C28H33ClN2
Histabutyzine Hydrochloride
RX_link
No information avaliable
Histabutyzine Hydrochloride
fda sheet
Histabutyzine Hydrochloride
msds (material safety sheet)
Histabutyzine Hydrochloride
Synthesis Reference
No information avaliable
Histabutyzine Hydrochloride
Molecular Weight
433.028 g/mol
Histabutyzine Hydrochloride
Melting Point
218 oC (BP)
Histabutyzine Hydrochloride
H2O Solubility
No information avaliable
Histabutyzine Hydrochloride
State
Liquid
Histabutyzine Hydrochloride
LogP
7.749
Histabutyzine Hydrochloride
Dosage Forms
Tablet (50 mg)
Histabutyzine Hydrochloride
Indication
For prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness and vertigo (dizziness caused by other medical problems).
Histabutyzine Hydrochloride
Pharmacology
Buclizine is a piperazine-derivative antihistamine used as an antivertigo/antiemetic agent. Buclizine is used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus. Although the mechanism by which buclizine exerts its antiemetic and antivertigo effects has not been fully elucidated, its central anticholinergic properties are partially responsible. The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone. It also possesses anticholinergic, antihistaminic, central nervous system depressant, and local anesthetic effects.
Histabutyzine Hydrochloride
Absorption
Rapidly absorbed following oral administration.
Histabutyzine Hydrochloride
side effects and Toxicity
No information avaliable
Histabutyzine Hydrochloride
Patient Information
Histabutyzine Hydrochloride
Organisms Affected
Humans and other mammals