PharmacyCodes



Histabutizine en es it fr

Histabutizine Brand names, Histabutizine Analogs

Histabutizine Brand Names Mixture

  • No information avaliable

Histabutizine Chemical_Formula

C28H33ClN2

Histabutizine RX_link

No information avaliable

Histabutizine fda sheet

Histabutizine msds (material safety sheet)

Histabutizine Synthesis Reference

No information avaliable

Histabutizine Molecular Weight

433.028 g/mol

Histabutizine Melting Point

218 oC (BP)

Histabutizine H2O Solubility

No information avaliable

Histabutizine State

Liquid

Histabutizine LogP

7.749

Histabutizine Dosage Forms

Tablet (50 mg)

Histabutizine Indication

For prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness and vertigo (dizziness caused by other medical problems).

Histabutizine Pharmacology

Buclizine is a piperazine-derivative antihistamine used as an antivertigo/antiemetic agent. Buclizine is used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus. Although the mechanism by which buclizine exerts its antiemetic and antivertigo effects has not been fully elucidated, its central anticholinergic properties are partially responsible. The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone. It also possesses anticholinergic, antihistaminic, central nervous system depressant, and local anesthetic effects.

Histabutizine Absorption

Rapidly absorbed following oral administration.

Histabutizine side effects and Toxicity

No information avaliable

Histabutizine Patient Information

Histabutizine Organisms Affected

Humans and other mammals