PharmacyCodes



Aphilan-R Base en es it fr

Aphilan-R Base Brand names, Aphilan-R Base Analogs

Aphilan-R Base Brand Names Mixture

  • No information avaliable

Aphilan-R Base Chemical_Formula

C28H33ClN2

Aphilan-R Base RX_link

No information avaliable

Aphilan-R Base fda sheet

Aphilan-R Base msds (material safety sheet)

Aphilan-R Base Synthesis Reference

No information avaliable

Aphilan-R Base Molecular Weight

433.028 g/mol

Aphilan-R Base Melting Point

218 oC (BP)

Aphilan-R Base H2O Solubility

No information avaliable

Aphilan-R Base State

Liquid

Aphilan-R Base LogP

7.749

Aphilan-R Base Dosage Forms

Tablet (50 mg)

Aphilan-R Base Indication

For prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness and vertigo (dizziness caused by other medical problems).

Aphilan-R Base Pharmacology

Buclizine is a piperazine-derivative antihistamine used as an antivertigo/antiemetic agent. Buclizine is used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus. Although the mechanism by which buclizine exerts its antiemetic and antivertigo effects has not been fully elucidated, its central anticholinergic properties are partially responsible. The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone. It also possesses anticholinergic, antihistaminic, central nervous system depressant, and local anesthetic effects.

Aphilan-R Base Absorption

Rapidly absorbed following oral administration.

Aphilan-R Base side effects and Toxicity

No information avaliable

Aphilan-R Base Patient Information

Aphilan-R Base Organisms Affected

Humans and other mammals