Aphilan-R Base
Aphilan-R Base Brand names, Aphilan-R Base Analogs
- Aphilan R
- Aphilan-R Base
- Bucladin
- Bucladin-S
- Buclifen
- Buclina
- Buclizina [Inn-Spanish]
- Buclizine Dihydrochloride
- Buclizine Hydrochloride
- Buclizine, Hydrochloride
- Buclizinum [Inn-Latin]
- Buclodin
- Histabuticine
- Histabutizine
- Histabutyzine
- Histabutyzine Dihydrochloride
- Histabutyzine Hydrochloride
- Hitabutyzyne
- Longifene
- Posdel
- Postafen
- Softran
- Vibazine
- Vibazine Hydrochloride
Aphilan-R Base Brand Names Mixture
- No information avaliable
Aphilan-R Base Chemical_Formula
C28H33ClN2
Aphilan-R Base RX_link
No information avaliable
Aphilan-R Base fda sheet
Aphilan-R Base msds (material safety sheet)
Aphilan-R Base Synthesis Reference
No information avaliable
Aphilan-R Base Molecular Weight
433.028 g/mol
Aphilan-R Base Melting Point
218 oC (BP)
Aphilan-R Base H2O Solubility
No information avaliable
Aphilan-R Base State
Liquid
Aphilan-R Base LogP
7.749
Aphilan-R Base Dosage Forms
Tablet (50 mg)
Aphilan-R Base Indication
For prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness and vertigo (dizziness caused by other medical problems).
Aphilan-R Base Pharmacology
Buclizine is a piperazine-derivative antihistamine used as an antivertigo/antiemetic agent. Buclizine is used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus. Although the mechanism by which buclizine exerts its antiemetic and antivertigo effects has not been fully elucidated, its central anticholinergic properties are partially responsible. The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone. It also possesses anticholinergic, antihistaminic, central nervous system depressant, and local anesthetic effects.
Aphilan-R Base Absorption
Rapidly absorbed following oral administration.
Aphilan-R Base side effects and Toxicity
No information avaliable
Aphilan-R Base Patient Information
Aphilan-R Base Organisms Affected
Humans and other mammals
