Buclizine Dihydrochloride
Buclizine Dihydrochloride Brand names, Buclizine Dihydrochloride Analogs
- Aphilan R
- Aphilan-R Base
- Bucladin
- Bucladin-S
- Buclifen
- Buclina
- Buclizina [Inn-Spanish]
- Buclizine Dihydrochloride
- Buclizine Hydrochloride
- Buclizine, Hydrochloride
- Buclizinum [Inn-Latin]
- Buclodin
- Histabuticine
- Histabutizine
- Histabutyzine
- Histabutyzine Dihydrochloride
- Histabutyzine Hydrochloride
- Hitabutyzyne
- Longifene
- Posdel
- Postafen
- Softran
- Vibazine
- Vibazine Hydrochloride
Buclizine Dihydrochloride Brand Names Mixture
- No information avaliable
Buclizine Dihydrochloride Chemical_Formula
C28H33ClN2
Buclizine Dihydrochloride RX_link
No information avaliable
Buclizine Dihydrochloride fda sheet
Buclizine Dihydrochloride msds (material safety sheet)
Buclizine Dihydrochloride Synthesis Reference
No information avaliable
Buclizine Dihydrochloride Molecular Weight
433.028 g/mol
Buclizine Dihydrochloride Melting Point
218 oC (BP)
Buclizine Dihydrochloride H2O Solubility
No information avaliable
Buclizine Dihydrochloride State
Liquid
Buclizine Dihydrochloride LogP
7.749
Buclizine Dihydrochloride Dosage Forms
Tablet (50 mg)
Buclizine Dihydrochloride Indication
For prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness and vertigo (dizziness caused by other medical problems).
Buclizine Dihydrochloride Pharmacology
Buclizine is a piperazine-derivative antihistamine used as an antivertigo/antiemetic agent. Buclizine is used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus. Although the mechanism by which buclizine exerts its antiemetic and antivertigo effects has not been fully elucidated, its central anticholinergic properties are partially responsible. The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone. It also possesses anticholinergic, antihistaminic, central nervous system depressant, and local anesthetic effects.
Buclizine Dihydrochloride Absorption
Rapidly absorbed following oral administration.
Buclizine Dihydrochloride side effects and Toxicity
No information avaliable
Buclizine Dihydrochloride Patient Information
Buclizine Dihydrochloride Organisms Affected
Humans and other mammals
