Buclodin
Brand names,
Buclodin
Analogs
Buclodin
Brand Names Mixture
Buclodin
Chemical_Formula
C28H33ClN2
Buclodin
RX_link
No information avaliable
Buclodin
fda sheet
Buclodin
msds (material safety sheet)
Buclodin
Synthesis Reference
No information avaliable
Buclodin
Molecular Weight
433.028 g/mol
Buclodin
Melting Point
218 oC (BP)
Buclodin
H2O Solubility
No information avaliable
Buclodin
State
Liquid
Buclodin
LogP
7.749
Buclodin
Dosage Forms
Tablet (50 mg)
Buclodin
Indication
For prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness and vertigo (dizziness caused by other medical problems).
Buclodin
Pharmacology
Buclizine is a piperazine-derivative antihistamine used as an antivertigo/antiemetic agent. Buclizine is used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus. Although the mechanism by which buclizine exerts its antiemetic and antivertigo effects has not been fully elucidated, its central anticholinergic properties are partially responsible. The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone. It also possesses anticholinergic, antihistaminic, central nervous system depressant, and local anesthetic effects.
Buclodin
Absorption
Rapidly absorbed following oral administration.
Buclodin
side effects and Toxicity
No information avaliable
Buclodin
Patient Information
Buclodin
Organisms Affected
Humans and other mammals