Posdel
Posdel Brand names, Posdel Analogs
- Aphilan R
- Aphilan-R Base
- Bucladin
- Bucladin-S
- Buclifen
- Buclina
- Buclizina [Inn-Spanish]
- Buclizine Dihydrochloride
- Buclizine Hydrochloride
- Buclizine, Hydrochloride
- Buclizinum [Inn-Latin]
- Buclodin
- Histabuticine
- Histabutizine
- Histabutyzine
- Histabutyzine Dihydrochloride
- Histabutyzine Hydrochloride
- Hitabutyzyne
- Longifene
- Posdel
- Postafen
- Softran
- Vibazine
- Vibazine Hydrochloride
Posdel Brand Names Mixture
- No information avaliable
Posdel Chemical_Formula
C28H33ClN2
Posdel RX_link
No information avaliable
Posdel fda sheet
Posdel msds (material safety sheet)
Posdel Synthesis Reference
No information avaliable
Posdel Molecular Weight
433.028 g/mol
Posdel Melting Point
218 oC (BP)
Posdel H2O Solubility
No information avaliable
Posdel State
Liquid
Posdel LogP
7.749
Posdel Dosage Forms
Tablet (50 mg)
Posdel Indication
For prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness and vertigo (dizziness caused by other medical problems).
Posdel Pharmacology
Buclizine is a piperazine-derivative antihistamine used as an antivertigo/antiemetic agent. Buclizine is used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus. Although the mechanism by which buclizine exerts its antiemetic and antivertigo effects has not been fully elucidated, its central anticholinergic properties are partially responsible. The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone. It also possesses anticholinergic, antihistaminic, central nervous system depressant, and local anesthetic effects.
Posdel Absorption
Rapidly absorbed following oral administration.
Posdel side effects and Toxicity
No information avaliable
Posdel Patient Information
Posdel Organisms Affected
Humans and other mammals
