Buclina

• Antiemetics
• Antihistamine
• Anticholinergic
• ATC:R06AE01

• Aphilan R
• Aphilan-R Base
• Bucladin
• Bucladin-S
• Buclifen
• Buclina
• Buclizina [Inn-Spanish]
• Buclizine Dihydrochloride
• Buclizine Hydrochloride
• Buclizine, Hydrochloride
• Buclizinum [Inn-Latin]
• Buclodin
• Histabuticine
• Histabutizine
• Histabutyzine
• Histabutyzine Dihydrochloride
• Histabutyzine Hydrochloride
• Hitabutyzyne
• Longifene
• Posdel
• Postafen
• Softran
• Vibazine
• Vibazine Hydrochloride

• No information avaliable

C₂₈H₃₃ClN₂

No information avaliable

No information avaliable

433.028 g/mol

218 ^oC (BP)

No information avaliable

Liquid

7.749

Tablet (50 mg)

For prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness and vertigo (dizziness caused by other medical problems).

Buclizine is a piperazine-derivative antihistamine used as an antivertigo/antiemetic agent. Buclizine is used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus. Although the mechanism by which buclizine exerts its antiemetic and antivertigo effects has not been fully elucidated, its central anticholinergic properties are partially responsible. The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone. It also possesses anticholinergic, antihistaminic, central nervous system depressant, and local anesthetic effects.

Rapidly absorbed following oral administration.

No information avaliable

Humans and other mammals