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Buclina Brand names, Buclina Analogs

Buclina Brand Names Mixture

  • No information avaliable

Buclina Chemical_Formula

C28H33ClN2

Buclina RX_link

No information avaliable

Buclina fda sheet

Buclina msds (material safety sheet)

Buclina Synthesis Reference

No information avaliable

Buclina Molecular Weight

433.028 g/mol

Buclina Melting Point

218 oC (BP)

Buclina H2O Solubility

No information avaliable

Buclina State

Liquid

Buclina LogP

7.749

Buclina Dosage Forms

Tablet (50 mg)

Buclina Indication

For prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness and vertigo (dizziness caused by other medical problems).

Buclina Pharmacology

Buclizine is a piperazine-derivative antihistamine used as an antivertigo/antiemetic agent. Buclizine is used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus. Although the mechanism by which buclizine exerts its antiemetic and antivertigo effects has not been fully elucidated, its central anticholinergic properties are partially responsible. The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone. It also possesses anticholinergic, antihistaminic, central nervous system depressant, and local anesthetic effects.

Buclina Absorption

Rapidly absorbed following oral administration.

Buclina side effects and Toxicity

No information avaliable

Buclina Patient Information

Buclina Organisms Affected

Humans and other mammals