Buclizine, Hydrochloride
Buclizine, Hydrochloride Brand names, Buclizine, Hydrochloride Analogs
- Aphilan R
- Aphilan-R Base
- Bucladin
- Bucladin-S
- Buclifen
- Buclina
- Buclizina [Inn-Spanish]
- Buclizine Dihydrochloride
- Buclizine Hydrochloride
- Buclizine, Hydrochloride
- Buclizinum [Inn-Latin]
- Buclodin
- Histabuticine
- Histabutizine
- Histabutyzine
- Histabutyzine Dihydrochloride
- Histabutyzine Hydrochloride
- Hitabutyzyne
- Longifene
- Posdel
- Postafen
- Softran
- Vibazine
- Vibazine Hydrochloride
Buclizine, Hydrochloride Brand Names Mixture
- No information avaliable
Buclizine, Hydrochloride Chemical_Formula
C28H33ClN2
Buclizine, Hydrochloride RX_link
No information avaliable
Buclizine, Hydrochloride fda sheet
Buclizine, Hydrochloride msds (material safety sheet)
Buclizine, Hydrochloride Synthesis Reference
No information avaliable
Buclizine, Hydrochloride Molecular Weight
433.028 g/mol
Buclizine, Hydrochloride Melting Point
218 oC (BP)
Buclizine, Hydrochloride H2O Solubility
No information avaliable
Buclizine, Hydrochloride State
Liquid
Buclizine, Hydrochloride LogP
7.749
Buclizine, Hydrochloride Dosage Forms
Tablet (50 mg)
Buclizine, Hydrochloride Indication
For prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness and vertigo (dizziness caused by other medical problems).
Buclizine, Hydrochloride Pharmacology
Buclizine is a piperazine-derivative antihistamine used as an antivertigo/antiemetic agent. Buclizine is used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus. Although the mechanism by which buclizine exerts its antiemetic and antivertigo effects has not been fully elucidated, its central anticholinergic properties are partially responsible. The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone. It also possesses anticholinergic, antihistaminic, central nervous system depressant, and local anesthetic effects.
Buclizine, Hydrochloride Absorption
Rapidly absorbed following oral administration.
Buclizine, Hydrochloride side effects and Toxicity
No information avaliable
Buclizine, Hydrochloride Patient Information
Buclizine, Hydrochloride Organisms Affected
Humans and other mammals
