Buclizine, Hydrochloride en es it fr

Buclizine, Hydrochloride Brand names, Buclizine, Hydrochloride Analogs

Buclizine, Hydrochloride Brand Names Mixture

  • No information avaliable

Buclizine, Hydrochloride Chemical_Formula

C28H33ClN2

Buclizine, Hydrochloride RX_link

No information avaliable

Buclizine, Hydrochloride fda sheet

Buclizine, Hydrochloride msds (material safety sheet)

Buclizine, Hydrochloride Synthesis Reference

No information avaliable

Buclizine, Hydrochloride Molecular Weight

433.028 g/mol

Buclizine, Hydrochloride Melting Point

218 oC (BP)

Buclizine, Hydrochloride H2O Solubility

No information avaliable

Buclizine, Hydrochloride State

Liquid

Buclizine, Hydrochloride LogP

7.749

Buclizine, Hydrochloride Dosage Forms

Tablet (50 mg)

Buclizine, Hydrochloride Indication

For prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness and vertigo (dizziness caused by other medical problems).

Buclizine, Hydrochloride Pharmacology

Buclizine is a piperazine-derivative antihistamine used as an antivertigo/antiemetic agent. Buclizine is used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus. Although the mechanism by which buclizine exerts its antiemetic and antivertigo effects has not been fully elucidated, its central anticholinergic properties are partially responsible. The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone. It also possesses anticholinergic, antihistaminic, central nervous system depressant, and local anesthetic effects.

Buclizine, Hydrochloride Absorption

Rapidly absorbed following oral administration.

Buclizine, Hydrochloride side effects and Toxicity

No information avaliable

Buclizine, Hydrochloride Patient Information

Buclizine, Hydrochloride Organisms Affected

Humans and other mammals