Turpinal SL
Brand names,
Turpinal SL
Analogs
Turpinal SL
Brand Names Mixture
Turpinal SL
Chemical_Formula
C24H25NO4
Turpinal SL
RX_link
http://www.rxlist.com/cgi/generic3/flavoxate.htm
Turpinal SL
fda sheet
Turpinal SL
msds (material safety sheet)
Turpinal SL
Synthesis Reference
No information avaliable
Turpinal SL
Molecular Weight
391.46 g/mol
Turpinal SL
Melting Point
No information avaliable
Turpinal SL
H2O Solubility
10 mg/L
Turpinal SL
State
Solid
Turpinal SL
LogP
4.636
Turpinal SL
Dosage Forms
Tablets (100 mg)
Turpinal SL
Indication
For symptomatic relief of dysuria, urgency, nocturia, suprapubic pain, frequency and incontinence as may occur in cystitis, prostatitis, urethritis, urethrocystitis/urethrotrigonitis.
Turpinal SL
Pharmacology
Flavoxate is a spasmolytic flavone derivative that acts by relaxing the smooth muscle in the urinary tract. Flavoxate is a competitive muscarinic receptor antagonist indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency. Muscarinic receptors play an important role in several major cholin-ergically mediated functions, including contractions of urinary bladder smooth muscle and stimulation of salivary secretion.
Turpinal SL
Absorption
Well absorbed from gastrointestinal tract.
Turpinal SL
side effects and Toxicity
The oral LD50 for flavoxate HCl in rats is 4273 mg/kg. The oral LD50 for flavoxate HCl in mice is 1837 mg/kg. Symptoms of overdose include convulsions, decreased ability to sweat, (warm, red skin, dry mouth, and increased body temperature), hallucinations, increased heart rate and blood pressure, and mental confusion.
Turpinal SL
Patient Information
Turpinal SL
Organisms Affected
Humans and other mammals