Oxyethylidenediphosphonic acid
Brand names,
Oxyethylidenediphosphonic acid
Analogs
Oxyethylidenediphosphonic acid
Brand Names Mixture
Oxyethylidenediphosphonic acid
Chemical_Formula
C24H25NO4
Oxyethylidenediphosphonic acid
RX_link
http://www.rxlist.com/cgi/generic3/flavoxate.htm
Oxyethylidenediphosphonic acid
fda sheet
Oxyethylidenediphosphonic acid
msds (material safety sheet)
Oxyethylidenediphosphonic acid
Synthesis Reference
No information avaliable
Oxyethylidenediphosphonic acid
Molecular Weight
391.46 g/mol
Oxyethylidenediphosphonic acid
Melting Point
No information avaliable
Oxyethylidenediphosphonic acid
H2O Solubility
10 mg/L
Oxyethylidenediphosphonic acid
State
Solid
Oxyethylidenediphosphonic acid
LogP
4.636
Oxyethylidenediphosphonic acid
Dosage Forms
Tablets (100 mg)
Oxyethylidenediphosphonic acid
Indication
For symptomatic relief of dysuria, urgency, nocturia, suprapubic pain, frequency and incontinence as may occur in cystitis, prostatitis, urethritis, urethrocystitis/urethrotrigonitis.
Oxyethylidenediphosphonic acid
Pharmacology
Flavoxate is a spasmolytic flavone derivative that acts by relaxing the smooth muscle in the urinary tract. Flavoxate is a competitive muscarinic receptor antagonist indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency. Muscarinic receptors play an important role in several major cholin-ergically mediated functions, including contractions of urinary bladder smooth muscle and stimulation of salivary secretion.
Oxyethylidenediphosphonic acid
Absorption
Well absorbed from gastrointestinal tract.
Oxyethylidenediphosphonic acid
side effects and Toxicity
The oral LD50 for flavoxate HCl in rats is 4273 mg/kg. The oral LD50 for flavoxate HCl in mice is 1837 mg/kg. Symptoms of overdose include convulsions, decreased ability to sweat, (warm, red skin, dry mouth, and increased body temperature), hallucinations, increased heart rate and blood pressure, and mental confusion.
Oxyethylidenediphosphonic acid
Patient Information
Oxyethylidenediphosphonic acid
Organisms Affected
Humans and other mammals