Etidronate Disodium
Brand names,
Etidronate Disodium
Analogs
Etidronate Disodium
Brand Names Mixture
Etidronate Disodium
Chemical_Formula
C24H25NO4
Etidronate Disodium
RX_link
http://www.rxlist.com/cgi/generic3/flavoxate.htm
Etidronate Disodium
fda sheet
Etidronate Disodium
msds (material safety sheet)
Etidronate Disodium
Synthesis Reference
No information avaliable
Etidronate Disodium
Molecular Weight
391.46 g/mol
Etidronate Disodium
Melting Point
No information avaliable
Etidronate Disodium
H2O Solubility
10 mg/L
Etidronate Disodium
State
Solid
Etidronate Disodium
LogP
4.636
Etidronate Disodium
Dosage Forms
Tablets (100 mg)
Etidronate Disodium
Indication
For symptomatic relief of dysuria, urgency, nocturia, suprapubic pain, frequency and incontinence as may occur in cystitis, prostatitis, urethritis, urethrocystitis/urethrotrigonitis.
Etidronate Disodium
Pharmacology
Flavoxate is a spasmolytic flavone derivative that acts by relaxing the smooth muscle in the urinary tract. Flavoxate is a competitive muscarinic receptor antagonist indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency. Muscarinic receptors play an important role in several major cholin-ergically mediated functions, including contractions of urinary bladder smooth muscle and stimulation of salivary secretion.
Etidronate Disodium
Absorption
Well absorbed from gastrointestinal tract.
Etidronate Disodium
side effects and Toxicity
The oral LD50 for flavoxate HCl in rats is 4273 mg/kg. The oral LD50 for flavoxate HCl in mice is 1837 mg/kg. Symptoms of overdose include convulsions, decreased ability to sweat, (warm, red skin, dry mouth, and increased body temperature), hallucinations, increased heart rate and blood pressure, and mental confusion.
Etidronate Disodium
Patient Information
Etidronate Disodium
Organisms Affected
Humans and other mammals