Didronel IV
Brand names,
Didronel IV
Analogs
Didronel IV
Brand Names Mixture
Didronel IV
Chemical_Formula
C24H25NO4
Didronel IV
RX_link
http://www.rxlist.com/cgi/generic3/flavoxate.htm
Didronel IV
fda sheet
Didronel IV
msds (material safety sheet)
Didronel IV
Synthesis Reference
No information avaliable
Didronel IV
Molecular Weight
391.46 g/mol
Didronel IV
Melting Point
No information avaliable
Didronel IV
H2O Solubility
10 mg/L
Didronel IV
State
Solid
Didronel IV
LogP
4.636
Didronel IV
Dosage Forms
Tablets (100 mg)
Didronel IV
Indication
For symptomatic relief of dysuria, urgency, nocturia, suprapubic pain, frequency and incontinence as may occur in cystitis, prostatitis, urethritis, urethrocystitis/urethrotrigonitis.
Didronel IV
Pharmacology
Flavoxate is a spasmolytic flavone derivative that acts by relaxing the smooth muscle in the urinary tract. Flavoxate is a competitive muscarinic receptor antagonist indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency. Muscarinic receptors play an important role in several major cholin-ergically mediated functions, including contractions of urinary bladder smooth muscle and stimulation of salivary secretion.
Didronel IV
Absorption
Well absorbed from gastrointestinal tract.
Didronel IV
side effects and Toxicity
The oral LD50 for flavoxate HCl in rats is 4273 mg/kg. The oral LD50 for flavoxate HCl in mice is 1837 mg/kg. Symptoms of overdose include convulsions, decreased ability to sweat, (warm, red skin, dry mouth, and increased body temperature), hallucinations, increased heart rate and blood pressure, and mental confusion.
Didronel IV
Patient Information
Didronel IV
Organisms Affected
Humans and other mammals