MPI Stannous Diphosphonate
Brand names,
MPI Stannous Diphosphonate
Analogs
MPI Stannous Diphosphonate
Brand Names Mixture
MPI Stannous Diphosphonate
Chemical_Formula
C24H25NO4
MPI Stannous Diphosphonate
RX_link
http://www.rxlist.com/cgi/generic3/flavoxate.htm
MPI Stannous Diphosphonate
fda sheet
MPI Stannous Diphosphonate
msds (material safety sheet)
MPI Stannous Diphosphonate
Synthesis Reference
No information avaliable
MPI Stannous Diphosphonate
Molecular Weight
391.46 g/mol
MPI Stannous Diphosphonate
Melting Point
No information avaliable
MPI Stannous Diphosphonate
H2O Solubility
10 mg/L
MPI Stannous Diphosphonate
State
Solid
MPI Stannous Diphosphonate
LogP
4.636
MPI Stannous Diphosphonate
Dosage Forms
Tablets (100 mg)
MPI Stannous Diphosphonate
Indication
For symptomatic relief of dysuria, urgency, nocturia, suprapubic pain, frequency and incontinence as may occur in cystitis, prostatitis, urethritis, urethrocystitis/urethrotrigonitis.
MPI Stannous Diphosphonate
Pharmacology
Flavoxate is a spasmolytic flavone derivative that acts by relaxing the smooth muscle in the urinary tract. Flavoxate is a competitive muscarinic receptor antagonist indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency. Muscarinic receptors play an important role in several major cholin-ergically mediated functions, including contractions of urinary bladder smooth muscle and stimulation of salivary secretion.
MPI Stannous Diphosphonate
Absorption
Well absorbed from gastrointestinal tract.
MPI Stannous Diphosphonate
side effects and Toxicity
The oral LD50 for flavoxate HCl in rats is 4273 mg/kg. The oral LD50 for flavoxate HCl in mice is 1837 mg/kg. Symptoms of overdose include convulsions, decreased ability to sweat, (warm, red skin, dry mouth, and increased body temperature), hallucinations, increased heart rate and blood pressure, and mental confusion.
MPI Stannous Diphosphonate
Patient Information
MPI Stannous Diphosphonate
Organisms Affected
Humans and other mammals