Etidronic acid
Brand names,
Etidronic acid
Analogs
Etidronic acid
Brand Names Mixture
Etidronic acid
Chemical_Formula
C24H25NO4
Etidronic acid
RX_link
http://www.rxlist.com/cgi/generic3/flavoxate.htm
Etidronic acid
fda sheet
Etidronic acid
msds (material safety sheet)
Etidronic acid
Synthesis Reference
No information avaliable
Etidronic acid
Molecular Weight
391.46 g/mol
Etidronic acid
Melting Point
No information avaliable
Etidronic acid
H2O Solubility
10 mg/L
Etidronic acid
State
Solid
Etidronic acid
LogP
4.636
Etidronic acid
Dosage Forms
Tablets (100 mg)
Etidronic acid
Indication
For symptomatic relief of dysuria, urgency, nocturia, suprapubic pain, frequency and incontinence as may occur in cystitis, prostatitis, urethritis, urethrocystitis/urethrotrigonitis.
Etidronic acid
Pharmacology
Flavoxate is a spasmolytic flavone derivative that acts by relaxing the smooth muscle in the urinary tract. Flavoxate is a competitive muscarinic receptor antagonist indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency. Muscarinic receptors play an important role in several major cholin-ergically mediated functions, including contractions of urinary bladder smooth muscle and stimulation of salivary secretion.
Etidronic acid
Absorption
Well absorbed from gastrointestinal tract.
Etidronic acid
side effects and Toxicity
The oral LD50 for flavoxate HCl in rats is 4273 mg/kg. The oral LD50 for flavoxate HCl in mice is 1837 mg/kg. Symptoms of overdose include convulsions, decreased ability to sweat, (warm, red skin, dry mouth, and increased body temperature), hallucinations, increased heart rate and blood pressure, and mental confusion.
Etidronic acid
Patient Information
Etidronic acid
Organisms Affected
Humans and other mammals