Acetodiphosphonic acid
Brand names,
Acetodiphosphonic acid
Analogs
Acetodiphosphonic acid
Brand Names Mixture
Acetodiphosphonic acid
Chemical_Formula
C24H25NO4
Acetodiphosphonic acid
RX_link
http://www.rxlist.com/cgi/generic3/flavoxate.htm
Acetodiphosphonic acid
fda sheet
Acetodiphosphonic acid
msds (material safety sheet)
Acetodiphosphonic acid
Synthesis Reference
No information avaliable
Acetodiphosphonic acid
Molecular Weight
391.46 g/mol
Acetodiphosphonic acid
Melting Point
No information avaliable
Acetodiphosphonic acid
H2O Solubility
10 mg/L
Acetodiphosphonic acid
State
Solid
Acetodiphosphonic acid
LogP
4.636
Acetodiphosphonic acid
Dosage Forms
Tablets (100 mg)
Acetodiphosphonic acid
Indication
For symptomatic relief of dysuria, urgency, nocturia, suprapubic pain, frequency and incontinence as may occur in cystitis, prostatitis, urethritis, urethrocystitis/urethrotrigonitis.
Acetodiphosphonic acid
Pharmacology
Flavoxate is a spasmolytic flavone derivative that acts by relaxing the smooth muscle in the urinary tract. Flavoxate is a competitive muscarinic receptor antagonist indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency. Muscarinic receptors play an important role in several major cholin-ergically mediated functions, including contractions of urinary bladder smooth muscle and stimulation of salivary secretion.
Acetodiphosphonic acid
Absorption
Well absorbed from gastrointestinal tract.
Acetodiphosphonic acid
side effects and Toxicity
The oral LD50 for flavoxate HCl in rats is 4273 mg/kg. The oral LD50 for flavoxate HCl in mice is 1837 mg/kg. Symptoms of overdose include convulsions, decreased ability to sweat, (warm, red skin, dry mouth, and increased body temperature), hallucinations, increased heart rate and blood pressure, and mental confusion.
Acetodiphosphonic acid
Patient Information
Acetodiphosphonic acid
Organisms Affected
Humans and other mammals