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Norforms Brand names, Norforms Analogs

Norforms Brand Names Mixture

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Norforms Chemical_Formula


Norforms RX_link

Norforms fda sheet

Norforms msds (material safety sheet)

Norforms MSDS

Norforms Synthesis Reference

A. Stoll et al., eidem, Helv. Chim. Acta. 26, 944 (1943)

Norforms Molecular Weight

339.432 g/mol

Norforms Melting Point

172 oC

Norforms H2O Solubility

25 mg/mL

Norforms State


Norforms LogP


Norforms Dosage Forms

Injection (intramuscular or intravenous); Tablet

Norforms Indication

For the prevention and control of excessive bleeding following vaginal childbirth

Norforms Pharmacology

Methylergonovine is a semisynthetic ergot alkaloid and a derivative of ergonovine and is used for the prevention and control of postpartum and post-abortion hemorrhage. In general, the effects of all the ergot alkaloids appear to results from their actions as partial agonists or antagonists at adrenergic, dopaminergic, and tryptaminergic receptors. The spectrum of effects depends on the agent, dosage, species, tissue, and experimental or physiological conditions. All of the alkaloids of ergot significantly increase the motor activity of the uterus. After small doses contractions are increased in force or frequency, or both, but are followed by a normal degree of relaxation. As the dose is increased, contractions become more forceful and prolonged, resting tonus is markedly increased, and sustained contracture can result.

Norforms Absorption

Absorption is rapid after oral (60% bioavailability) and intramuscular (78% bioavailability) administration.

Norforms side effects and Toxicity

Signs and symptoms of overexposure: hypertension, seizures, headache, hypotension, nausea, and vomiting.

Norforms Patient Information

Norforms Organisms Affected

Humans and other mammals