Mephenamic Acid
Brand names,
Mephenamic Acid
Analogs
Mephenamic Acid
Brand Names Mixture
Mephenamic Acid
Chemical_Formula
C15H15NO2
Mephenamic Acid
RX_link
http://www.rxlist.com/cgi/generic3/mefenamic.htm
Mephenamic Acid
fda sheet
Mephenamic Acid
msds (material safety sheet)
Mephenamic Acid
Synthesis Reference
No information avaliable
Mephenamic Acid
Molecular Weight
241.285 g/mol
Mephenamic Acid
Melting Point
230-231 oC
Mephenamic Acid
H2O Solubility
20 mg/L
Mephenamic Acid
State
Solid
Mephenamic Acid
LogP
4.041
Mephenamic Acid
Dosage Forms
Bolus; Capsule; Capsule (enteric-coated); Drops; Liquid; Lotion; Powder; Powder for solution; Shampoo; Soap bar; Solution; Stick; Syrup; Tablet; Tablet (extended-release)
Mephenamic Acid
Indication
For the treatment of rheumatoid arthritis, osteoarthritis, dysmenorrhea, and mild to moderate pain, inflammation, and fever.
Mephenamic Acid
Pharmacology
Mefenamic acid, an anthranilic acid derivative, is a member of the fenamate group of nonsteroidal anti-inflammatory drugs (NSAIDs). It exhibits anti-inflammatory, analgesic, and antipyretic activities. Similar to other NSAIDs, mefenamic acid inhibits prostaglandin synthetase.
Mephenamic Acid
Absorption
Mefenamic acid is rapidly absorbed after oral administration.
Mephenamic Acid
side effects and Toxicity
Oral, rat LD50: 740 mg/kg. Symptoms of overdose may include severe stomach pain, coffee ground-like vomit, dark stool, ringing in the ears, change in amount of urine, unusually fast or slow heartbeat, muscle weakness, slow or shallow breathing, confusion, severe headache or loss of consciousness.
Mephenamic Acid
Patient Information
Mephenamic Acid
Organisms Affected
Humans and other mammals