In-M
In-M Brand names, In-M Analogs
In-M Brand Names Mixture
- No information avaliable
In-M Chemical_Formula
C15H15NO2
In-M RX_link
http://www.rxlist.com/cgi/generic3/mefenamic.htm
In-M fda sheet
In-M msds (material safety sheet)
In-M Synthesis Reference
No information avaliable
In-M Molecular Weight
241.285 g/mol
In-M Melting Point
230-231 oC
In-M H2O Solubility
20 mg/L
In-M State
Solid
In-M LogP
4.041
In-M Dosage Forms
Bolus; Capsule; Capsule (enteric-coated); Drops; Liquid; Lotion; Powder; Powder for solution; Shampoo; Soap bar; Solution; Stick; Syrup; Tablet; Tablet (extended-release)
In-M Indication
For the treatment of rheumatoid arthritis, osteoarthritis, dysmenorrhea, and mild to moderate pain, inflammation, and fever.
In-M Pharmacology
Mefenamic acid, an anthranilic acid derivative, is a member of the fenamate group of nonsteroidal anti-inflammatory drugs (NSAIDs). It exhibits anti-inflammatory, analgesic, and antipyretic activities. Similar to other NSAIDs, mefenamic acid inhibits prostaglandin synthetase.
In-M Absorption
Mefenamic acid is rapidly absorbed after oral administration.
In-M side effects and Toxicity
Oral, rat LD50: 740 mg/kg. Symptoms of overdose may include severe stomach pain, coffee ground-like vomit, dark stool, ringing in the ears, change in amount of urine, unusually fast or slow heartbeat, muscle weakness, slow or shallow breathing, confusion, severe headache or loss of consciousness.
In-M Patient Information
In-M Organisms Affected
Humans and other mammals
