Mefenaminsaeure
Brand names,
Mefenaminsaeure
Analogs
Mefenaminsaeure
Brand Names Mixture
Mefenaminsaeure
Chemical_Formula
C15H15NO2
Mefenaminsaeure
RX_link
http://www.rxlist.com/cgi/generic3/mefenamic.htm
Mefenaminsaeure
fda sheet
Mefenaminsaeure
msds (material safety sheet)
Mefenaminsaeure
Synthesis Reference
No information avaliable
Mefenaminsaeure
Molecular Weight
241.285 g/mol
Mefenaminsaeure
Melting Point
230-231 oC
Mefenaminsaeure
H2O Solubility
20 mg/L
Mefenaminsaeure
State
Solid
Mefenaminsaeure
LogP
4.041
Mefenaminsaeure
Dosage Forms
Bolus; Capsule; Capsule (enteric-coated); Drops; Liquid; Lotion; Powder; Powder for solution; Shampoo; Soap bar; Solution; Stick; Syrup; Tablet; Tablet (extended-release)
Mefenaminsaeure
Indication
For the treatment of rheumatoid arthritis, osteoarthritis, dysmenorrhea, and mild to moderate pain, inflammation, and fever.
Mefenaminsaeure
Pharmacology
Mefenamic acid, an anthranilic acid derivative, is a member of the fenamate group of nonsteroidal anti-inflammatory drugs (NSAIDs). It exhibits anti-inflammatory, analgesic, and antipyretic activities. Similar to other NSAIDs, mefenamic acid inhibits prostaglandin synthetase.
Mefenaminsaeure
Absorption
Mefenamic acid is rapidly absorbed after oral administration.
Mefenaminsaeure
side effects and Toxicity
Oral, rat LD50: 740 mg/kg. Symptoms of overdose may include severe stomach pain, coffee ground-like vomit, dark stool, ringing in the ears, change in amount of urine, unusually fast or slow heartbeat, muscle weakness, slow or shallow breathing, confusion, severe headache or loss of consciousness.
Mefenaminsaeure
Patient Information
Mefenaminsaeure
Organisms Affected
Humans and other mammals