Parkemed
Brand names,
Parkemed
Analogs
Parkemed
Brand Names Mixture
Parkemed
Chemical_Formula
C15H15NO2
Parkemed
RX_link
http://www.rxlist.com/cgi/generic3/mefenamic.htm
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fda sheet
Parkemed
msds (material safety sheet)
Parkemed
Synthesis Reference
No information avaliable
Parkemed
Molecular Weight
241.285 g/mol
Parkemed
Melting Point
230-231 oC
Parkemed
H2O Solubility
20 mg/L
Parkemed
State
Solid
Parkemed
LogP
4.041
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Dosage Forms
Bolus; Capsule; Capsule (enteric-coated); Drops; Liquid; Lotion; Powder; Powder for solution; Shampoo; Soap bar; Solution; Stick; Syrup; Tablet; Tablet (extended-release)
Parkemed
Indication
For the treatment of rheumatoid arthritis, osteoarthritis, dysmenorrhea, and mild to moderate pain, inflammation, and fever.
Parkemed
Pharmacology
Mefenamic acid, an anthranilic acid derivative, is a member of the fenamate group of nonsteroidal anti-inflammatory drugs (NSAIDs). It exhibits anti-inflammatory, analgesic, and antipyretic activities. Similar to other NSAIDs, mefenamic acid inhibits prostaglandin synthetase.
Parkemed
Absorption
Mefenamic acid is rapidly absorbed after oral administration.
Parkemed
side effects and Toxicity
Oral, rat LD50: 740 mg/kg. Symptoms of overdose may include severe stomach pain, coffee ground-like vomit, dark stool, ringing in the ears, change in amount of urine, unusually fast or slow heartbeat, muscle weakness, slow or shallow breathing, confusion, severe headache or loss of consciousness.
Parkemed
Patient Information
Parkemed
Organisms Affected
Humans and other mammals