Mephenaminic Acid
Brand names,
Mephenaminic Acid
Analogs
Mephenaminic Acid
Brand Names Mixture
Mephenaminic Acid
Chemical_Formula
C15H15NO2
Mephenaminic Acid
RX_link
http://www.rxlist.com/cgi/generic3/mefenamic.htm
Mephenaminic Acid
fda sheet
Mephenaminic Acid
msds (material safety sheet)
Mephenaminic Acid
Synthesis Reference
No information avaliable
Mephenaminic Acid
Molecular Weight
241.285 g/mol
Mephenaminic Acid
Melting Point
230-231 oC
Mephenaminic Acid
H2O Solubility
20 mg/L
Mephenaminic Acid
State
Solid
Mephenaminic Acid
LogP
4.041
Mephenaminic Acid
Dosage Forms
Bolus; Capsule; Capsule (enteric-coated); Drops; Liquid; Lotion; Powder; Powder for solution; Shampoo; Soap bar; Solution; Stick; Syrup; Tablet; Tablet (extended-release)
Mephenaminic Acid
Indication
For the treatment of rheumatoid arthritis, osteoarthritis, dysmenorrhea, and mild to moderate pain, inflammation, and fever.
Mephenaminic Acid
Pharmacology
Mefenamic acid, an anthranilic acid derivative, is a member of the fenamate group of nonsteroidal anti-inflammatory drugs (NSAIDs). It exhibits anti-inflammatory, analgesic, and antipyretic activities. Similar to other NSAIDs, mefenamic acid inhibits prostaglandin synthetase.
Mephenaminic Acid
Absorption
Mefenamic acid is rapidly absorbed after oral administration.
Mephenaminic Acid
side effects and Toxicity
Oral, rat LD50: 740 mg/kg. Symptoms of overdose may include severe stomach pain, coffee ground-like vomit, dark stool, ringing in the ears, change in amount of urine, unusually fast or slow heartbeat, muscle weakness, slow or shallow breathing, confusion, severe headache or loss of consciousness.
Mephenaminic Acid
Patient Information
Mephenaminic Acid
Organisms Affected
Humans and other mammals