Mefacit
Brand names,
Mefacit
Analogs
Mefacit
Brand Names Mixture
Mefacit
Chemical_Formula
C15H15NO2
Mefacit
RX_link
http://www.rxlist.com/cgi/generic3/mefenamic.htm
Mefacit
fda sheet
Mefacit
msds (material safety sheet)
Mefacit
Synthesis Reference
No information avaliable
Mefacit
Molecular Weight
241.285 g/mol
Mefacit
Melting Point
230-231 oC
Mefacit
H2O Solubility
20 mg/L
Mefacit
State
Solid
Mefacit
LogP
4.041
Mefacit
Dosage Forms
Bolus; Capsule; Capsule (enteric-coated); Drops; Liquid; Lotion; Powder; Powder for solution; Shampoo; Soap bar; Solution; Stick; Syrup; Tablet; Tablet (extended-release)
Mefacit
Indication
For the treatment of rheumatoid arthritis, osteoarthritis, dysmenorrhea, and mild to moderate pain, inflammation, and fever.
Mefacit
Pharmacology
Mefenamic acid, an anthranilic acid derivative, is a member of the fenamate group of nonsteroidal anti-inflammatory drugs (NSAIDs). It exhibits anti-inflammatory, analgesic, and antipyretic activities. Similar to other NSAIDs, mefenamic acid inhibits prostaglandin synthetase.
Mefacit
Absorption
Mefenamic acid is rapidly absorbed after oral administration.
Mefacit
side effects and Toxicity
Oral, rat LD50: 740 mg/kg. Symptoms of overdose may include severe stomach pain, coffee ground-like vomit, dark stool, ringing in the ears, change in amount of urine, unusually fast or slow heartbeat, muscle weakness, slow or shallow breathing, confusion, severe headache or loss of consciousness.
Mefacit
Patient Information
Mefacit
Organisms Affected
Humans and other mammals