Ponstel
Brand names,
Ponstel
Analogs
Ponstel
Brand Names Mixture
Ponstel
Chemical_Formula
C15H15NO2
Ponstel
RX_link
http://www.rxlist.com/cgi/generic3/mefenamic.htm
Ponstel
fda sheet
Ponstel
msds (material safety sheet)
Ponstel
Synthesis Reference
No information avaliable
Ponstel
Molecular Weight
241.285 g/mol
Ponstel
Melting Point
230-231 oC
Ponstel
H2O Solubility
20 mg/L
Ponstel
State
Solid
Ponstel
LogP
4.041
Ponstel
Dosage Forms
Bolus; Capsule; Capsule (enteric-coated); Drops; Liquid; Lotion; Powder; Powder for solution; Shampoo; Soap bar; Solution; Stick; Syrup; Tablet; Tablet (extended-release)
Ponstel
Indication
For the treatment of rheumatoid arthritis, osteoarthritis, dysmenorrhea, and mild to moderate pain, inflammation, and fever.
Ponstel
Pharmacology
Mefenamic acid, an anthranilic acid derivative, is a member of the fenamate group of nonsteroidal anti-inflammatory drugs (NSAIDs). It exhibits anti-inflammatory, analgesic, and antipyretic activities. Similar to other NSAIDs, mefenamic acid inhibits prostaglandin synthetase.
Ponstel
Absorption
Mefenamic acid is rapidly absorbed after oral administration.
Ponstel
side effects and Toxicity
Oral, rat LD50: 740 mg/kg. Symptoms of overdose may include severe stomach pain, coffee ground-like vomit, dark stool, ringing in the ears, change in amount of urine, unusually fast or slow heartbeat, muscle weakness, slow or shallow breathing, confusion, severe headache or loss of consciousness.
Ponstel
Patient Information
Ponstel
Organisms Affected
Humans and other mammals