Acide Mefenamique
Brand names,
Acide Mefenamique
Analogs
Acide Mefenamique
Brand Names Mixture
Acide Mefenamique
Chemical_Formula
C15H15NO2
Acide Mefenamique
RX_link
http://www.rxlist.com/cgi/generic3/mefenamic.htm
Acide Mefenamique
fda sheet
Acide Mefenamique
msds (material safety sheet)
Acide Mefenamique
Synthesis Reference
No information avaliable
Acide Mefenamique
Molecular Weight
241.285 g/mol
Acide Mefenamique
Melting Point
230-231 oC
Acide Mefenamique
H2O Solubility
20 mg/L
Acide Mefenamique
State
Solid
Acide Mefenamique
LogP
4.041
Acide Mefenamique
Dosage Forms
Bolus; Capsule; Capsule (enteric-coated); Drops; Liquid; Lotion; Powder; Powder for solution; Shampoo; Soap bar; Solution; Stick; Syrup; Tablet; Tablet (extended-release)
Acide Mefenamique
Indication
For the treatment of rheumatoid arthritis, osteoarthritis, dysmenorrhea, and mild to moderate pain, inflammation, and fever.
Acide Mefenamique
Pharmacology
Mefenamic acid, an anthranilic acid derivative, is a member of the fenamate group of nonsteroidal anti-inflammatory drugs (NSAIDs). It exhibits anti-inflammatory, analgesic, and antipyretic activities. Similar to other NSAIDs, mefenamic acid inhibits prostaglandin synthetase.
Acide Mefenamique
Absorption
Mefenamic acid is rapidly absorbed after oral administration.
Acide Mefenamique
side effects and Toxicity
Oral, rat LD50: 740 mg/kg. Symptoms of overdose may include severe stomach pain, coffee ground-like vomit, dark stool, ringing in the ears, change in amount of urine, unusually fast or slow heartbeat, muscle weakness, slow or shallow breathing, confusion, severe headache or loss of consciousness.
Acide Mefenamique
Patient Information
Acide Mefenamique
Organisms Affected
Humans and other mammals