Methenamic Acid
Brand names,
Methenamic Acid
Analogs
Methenamic Acid
Brand Names Mixture
Methenamic Acid
Chemical_Formula
C15H15NO2
Methenamic Acid
RX_link
http://www.rxlist.com/cgi/generic3/mefenamic.htm
Methenamic Acid
fda sheet
Methenamic Acid
msds (material safety sheet)
Methenamic Acid
Synthesis Reference
No information avaliable
Methenamic Acid
Molecular Weight
241.285 g/mol
Methenamic Acid
Melting Point
230-231 oC
Methenamic Acid
H2O Solubility
20 mg/L
Methenamic Acid
State
Solid
Methenamic Acid
LogP
4.041
Methenamic Acid
Dosage Forms
Bolus; Capsule; Capsule (enteric-coated); Drops; Liquid; Lotion; Powder; Powder for solution; Shampoo; Soap bar; Solution; Stick; Syrup; Tablet; Tablet (extended-release)
Methenamic Acid
Indication
For the treatment of rheumatoid arthritis, osteoarthritis, dysmenorrhea, and mild to moderate pain, inflammation, and fever.
Methenamic Acid
Pharmacology
Mefenamic acid, an anthranilic acid derivative, is a member of the fenamate group of nonsteroidal anti-inflammatory drugs (NSAIDs). It exhibits anti-inflammatory, analgesic, and antipyretic activities. Similar to other NSAIDs, mefenamic acid inhibits prostaglandin synthetase.
Methenamic Acid
Absorption
Mefenamic acid is rapidly absorbed after oral administration.
Methenamic Acid
side effects and Toxicity
Oral, rat LD50: 740 mg/kg. Symptoms of overdose may include severe stomach pain, coffee ground-like vomit, dark stool, ringing in the ears, change in amount of urine, unusually fast or slow heartbeat, muscle weakness, slow or shallow breathing, confusion, severe headache or loss of consciousness.
Methenamic Acid
Patient Information
Methenamic Acid
Organisms Affected
Humans and other mammals