Mefenacid
Brand names,
Mefenacid
Analogs
Mefenacid
Brand Names Mixture
Mefenacid
Chemical_Formula
C15H15NO2
Mefenacid
RX_link
http://www.rxlist.com/cgi/generic3/mefenamic.htm
Mefenacid
fda sheet
Mefenacid
msds (material safety sheet)
Mefenacid
Synthesis Reference
No information avaliable
Mefenacid
Molecular Weight
241.285 g/mol
Mefenacid
Melting Point
230-231 oC
Mefenacid
H2O Solubility
20 mg/L
Mefenacid
State
Solid
Mefenacid
LogP
4.041
Mefenacid
Dosage Forms
Bolus; Capsule; Capsule (enteric-coated); Drops; Liquid; Lotion; Powder; Powder for solution; Shampoo; Soap bar; Solution; Stick; Syrup; Tablet; Tablet (extended-release)
Mefenacid
Indication
For the treatment of rheumatoid arthritis, osteoarthritis, dysmenorrhea, and mild to moderate pain, inflammation, and fever.
Mefenacid
Pharmacology
Mefenamic acid, an anthranilic acid derivative, is a member of the fenamate group of nonsteroidal anti-inflammatory drugs (NSAIDs). It exhibits anti-inflammatory, analgesic, and antipyretic activities. Similar to other NSAIDs, mefenamic acid inhibits prostaglandin synthetase.
Mefenacid
Absorption
Mefenamic acid is rapidly absorbed after oral administration.
Mefenacid
side effects and Toxicity
Oral, rat LD50: 740 mg/kg. Symptoms of overdose may include severe stomach pain, coffee ground-like vomit, dark stool, ringing in the ears, change in amount of urine, unusually fast or slow heartbeat, muscle weakness, slow or shallow breathing, confusion, severe headache or loss of consciousness.
Mefenacid
Patient Information
Mefenacid
Organisms Affected
Humans and other mammals