Coslan
Brand names,
Coslan
Analogs
Coslan
Brand Names Mixture
Coslan
Chemical_Formula
C15H15NO2
Coslan
RX_link
http://www.rxlist.com/cgi/generic3/mefenamic.htm
Coslan
fda sheet
Coslan
msds (material safety sheet)
Coslan
Synthesis Reference
No information avaliable
Coslan
Molecular Weight
241.285 g/mol
Coslan
Melting Point
230-231 oC
Coslan
H2O Solubility
20 mg/L
Coslan
State
Solid
Coslan
LogP
4.041
Coslan
Dosage Forms
Bolus; Capsule; Capsule (enteric-coated); Drops; Liquid; Lotion; Powder; Powder for solution; Shampoo; Soap bar; Solution; Stick; Syrup; Tablet; Tablet (extended-release)
Coslan
Indication
For the treatment of rheumatoid arthritis, osteoarthritis, dysmenorrhea, and mild to moderate pain, inflammation, and fever.
Coslan
Pharmacology
Mefenamic acid, an anthranilic acid derivative, is a member of the fenamate group of nonsteroidal anti-inflammatory drugs (NSAIDs). It exhibits anti-inflammatory, analgesic, and antipyretic activities. Similar to other NSAIDs, mefenamic acid inhibits prostaglandin synthetase.
Coslan
Absorption
Mefenamic acid is rapidly absorbed after oral administration.
Coslan
side effects and Toxicity
Oral, rat LD50: 740 mg/kg. Symptoms of overdose may include severe stomach pain, coffee ground-like vomit, dark stool, ringing in the ears, change in amount of urine, unusually fast or slow heartbeat, muscle weakness, slow or shallow breathing, confusion, severe headache or loss of consciousness.
Coslan
Patient Information
Coslan
Organisms Affected
Humans and other mammals