Ponstan
Brand names,
Ponstan
Analogs
Ponstan
Brand Names Mixture
Ponstan
Chemical_Formula
C15H15NO2
Ponstan
RX_link
http://www.rxlist.com/cgi/generic3/mefenamic.htm
Ponstan
fda sheet
Ponstan
msds (material safety sheet)
Ponstan
Synthesis Reference
No information avaliable
Ponstan
Molecular Weight
241.285 g/mol
Ponstan
Melting Point
230-231 oC
Ponstan
H2O Solubility
20 mg/L
Ponstan
State
Solid
Ponstan
LogP
4.041
Ponstan
Dosage Forms
Bolus; Capsule; Capsule (enteric-coated); Drops; Liquid; Lotion; Powder; Powder for solution; Shampoo; Soap bar; Solution; Stick; Syrup; Tablet; Tablet (extended-release)
Ponstan
Indication
For the treatment of rheumatoid arthritis, osteoarthritis, dysmenorrhea, and mild to moderate pain, inflammation, and fever.
Ponstan
Pharmacology
Mefenamic acid, an anthranilic acid derivative, is a member of the fenamate group of nonsteroidal anti-inflammatory drugs (NSAIDs). It exhibits anti-inflammatory, analgesic, and antipyretic activities. Similar to other NSAIDs, mefenamic acid inhibits prostaglandin synthetase.
Ponstan
Absorption
Mefenamic acid is rapidly absorbed after oral administration.
Ponstan
side effects and Toxicity
Oral, rat LD50: 740 mg/kg. Symptoms of overdose may include severe stomach pain, coffee ground-like vomit, dark stool, ringing in the ears, change in amount of urine, unusually fast or slow heartbeat, muscle weakness, slow or shallow breathing, confusion, severe headache or loss of consciousness.
Ponstan
Patient Information
Ponstan
Organisms Affected
Humans and other mammals