Mefanamic Acid
Brand names,
Mefanamic Acid
Analogs
Mefanamic Acid
Brand Names Mixture
Mefanamic Acid
Chemical_Formula
C15H15NO2
Mefanamic Acid
RX_link
http://www.rxlist.com/cgi/generic3/mefenamic.htm
Mefanamic Acid
fda sheet
Mefanamic Acid
msds (material safety sheet)
Mefanamic Acid
Synthesis Reference
No information avaliable
Mefanamic Acid
Molecular Weight
241.285 g/mol
Mefanamic Acid
Melting Point
230-231 oC
Mefanamic Acid
H2O Solubility
20 mg/L
Mefanamic Acid
State
Solid
Mefanamic Acid
LogP
4.041
Mefanamic Acid
Dosage Forms
Bolus; Capsule; Capsule (enteric-coated); Drops; Liquid; Lotion; Powder; Powder for solution; Shampoo; Soap bar; Solution; Stick; Syrup; Tablet; Tablet (extended-release)
Mefanamic Acid
Indication
For the treatment of rheumatoid arthritis, osteoarthritis, dysmenorrhea, and mild to moderate pain, inflammation, and fever.
Mefanamic Acid
Pharmacology
Mefenamic acid, an anthranilic acid derivative, is a member of the fenamate group of nonsteroidal anti-inflammatory drugs (NSAIDs). It exhibits anti-inflammatory, analgesic, and antipyretic activities. Similar to other NSAIDs, mefenamic acid inhibits prostaglandin synthetase.
Mefanamic Acid
Absorption
Mefenamic acid is rapidly absorbed after oral administration.
Mefanamic Acid
side effects and Toxicity
Oral, rat LD50: 740 mg/kg. Symptoms of overdose may include severe stomach pain, coffee ground-like vomit, dark stool, ringing in the ears, change in amount of urine, unusually fast or slow heartbeat, muscle weakness, slow or shallow breathing, confusion, severe headache or loss of consciousness.
Mefanamic Acid
Patient Information
Mefanamic Acid
Organisms Affected
Humans and other mammals