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Achromycin, Naphthacene Derivative en es it fr

Achromycin, Naphthacene Derivative Brand names, Achromycin, Naphthacene Derivative Analogs

Achromycin, Naphthacene Derivative Brand Names Mixture

  • Delta-Albaplex tablets (Novobiocin sodium + Prednisolone + Tetracycline hydrochloride)
  • Neo Chlor PWR (Neomycin sulfate + Tetracycline hydrochloride)
  • Neo-Chlor (Neomycin sulfate + Tetracycline hydrochloride)
  • Neotetramed PWR (Neomycin sulfate + Tetracycline hydrochloride)
  • P Onytricin P (Calcium D-pantothenate + Menadione sodium bisulfite + Nicotinamide + Tetracycline hydrochloride + Vitamin A + Vitamin B12 + Vitamin B2 + Vitamin B6 + Vitamin D3 + Vitamin E)

Achromycin, Naphthacene Derivative Chemical_Formula

C22H24N2O8

Achromycin, Naphthacene Derivative RX_link

http://www.rxlist.com/cgi/generic2/tetcycl2.htm

Achromycin, Naphthacene Derivative fda sheet

Achromycin, Naphthacene Derivative msds (material safety sheet)

Achromycin,_Naphthacene_Derivative MSDS

Achromycin, Naphthacene Derivative Synthesis Reference

J. H. Boothe et al., J. Am. Chem. Soc. 75, 4621 (1953)

Achromycin, Naphthacene Derivative Molecular Weight

444.435 g/mol

Achromycin, Naphthacene Derivative Melting Point

165oC

Achromycin, Naphthacene Derivative H2O Solubility

231 mg/L at 25 oC (SRC PhysProp experimental -- YALKOWSKY,SH & DANNENFELSER,RM (1992))

Achromycin, Naphthacene Derivative State

Solid

Achromycin, Naphthacene Derivative LogP

-0.304

Achromycin, Naphthacene Derivative Dosage Forms

Tablets; Oral suspension; Capsules; Topical solution; Ophthalmic suspension; IV injection; IM injection; Ointment

Achromycin, Naphthacene Derivative Indication

Used to treat bacterial infections such as Rocky Mountain spotted fever, typhus fever, and tick fevers; upper respiratory infections; pneumonia; gonorrhea; amoebic infections; and urinary tract infections. It is also used to help treat severe acne and to treat trachoma (a chronic eye infection) and conjunctivitis (pinkeye). Tetracycline is often an alternative drug for people who are allergic to penicillin.

Achromycin, Naphthacene Derivative Pharmacology

Tetracycline is a short-acting antibiotic semisynthetically produced from chlortetracycline, which is derived from Streptomyces aureofaciens. Tetracycline inhibits cell growth by inhibiting translation. It binds to the 30S ribosomal subunit and prevents the amino-acyl tRNA from binding to the A site of the ribosome. This binding is reversible in nature.

Achromycin, Naphthacene Derivative Absorption

Bioavailability is less than 40% when administered via intramuscular injection, 100% intravenously, and 60-80% orally (fasting adults). Food and/or milk reduce GI absorption of oral preparations of tetracycline by 50% or more.

Achromycin, Naphthacene Derivative side effects and Toxicity

LD50=808mg/kg (orally in mice)

Achromycin, Naphthacene Derivative Patient Information

Achromycin, Naphthacene Derivative Organisms Affected

Enteric bacteria and other eubacteria