Enterocycline
Enterocycline Brand names, Enterocycline Analogs
- Abramycin
- Abricycline
- Achromycin
- Achromycin V
- Achromycin, Naphthacene Derivative
- Actisite
- Agromicina
- Ambramicina
- Ambramycin
- Amycin
- Anhydrotetracycline
- Aureomycin
- Bio-Tetra
- Biocycline
- Bristaciclin
- Bristaciclin α
- Bristaciclina
- Bristacycline
- Cefracycline
- Ciclibion
- Copharlan
- Criseociclina
- Cyclomycin
- Cyclopar
- Cytome
- Democracin
- Deschlorobiomycin
- Dumocyclin
- Enterocycline
- Hostacyclin
- Lexacycline
- Limecycline
- Liquamycin
- Medocycline
- Mericycline
- Micycline
- Neocycline
- Oletetrin
- Omegamycin
- Orlycycline
- Oxytetracycline HCl
- Panmycin
- Polycycline
- Polyotic
- Purocyclina
- Resteclin
- Retet
- Robitet
- Roviciclina
- SK-Tetracycline
- Solvocin
- Sumycin
- Sumycin Syrup
- TAC
- TC
- Terramycin
- Tetra-CO
- Tetrabon
- Tetrachel
- Tetracycl
- Tetracycline HCl
- Tetracycline II
- Tetracyn
- Tetradecin
- Tetrafil
- Tetramed
- Tetraverine
- Tetrex
- Topicycline
- Tsiklomistsin
- Tsiklomitsin
- Veracin
- Vetacyclinum
Enterocycline Brand Names Mixture
- Delta-Albaplex tablets (Novobiocin sodium + Prednisolone + Tetracycline hydrochloride)
- Neo Chlor PWR (Neomycin sulfate + Tetracycline hydrochloride)
- Neo-Chlor (Neomycin sulfate + Tetracycline hydrochloride)
- Neotetramed PWR (Neomycin sulfate + Tetracycline hydrochloride)
- P Onytricin P (Calcium D-pantothenate + Menadione sodium bisulfite + Nicotinamide + Tetracycline hydrochloride + Vitamin A + Vitamin B12 + Vitamin B2 + Vitamin B6 + Vitamin D3 + Vitamin E)
Enterocycline Chemical_Formula
C22H24N2O8
Enterocycline RX_link
http://www.rxlist.com/cgi/generic2/tetcycl2.htm
Enterocycline fda sheet
Enterocycline msds (material safety sheet)
Enterocycline Synthesis Reference
J. H. Boothe et al., J. Am. Chem. Soc. 75, 4621 (1953)
Enterocycline Molecular Weight
444.435 g/mol
Enterocycline Melting Point
165oC
Enterocycline H2O Solubility
231 mg/L at 25 oC (SRC PhysProp experimental -- YALKOWSKY,SH & DANNENFELSER,RM (1992))
Enterocycline State
Solid
Enterocycline LogP
-0.304
Enterocycline Dosage Forms
Tablets; Oral suspension; Capsules; Topical solution; Ophthalmic suspension; IV injection; IM injection; Ointment
Enterocycline Indication
Used to treat bacterial infections such as Rocky Mountain spotted fever, typhus fever, and tick fevers; upper respiratory infections; pneumonia; gonorrhea; amoebic infections; and urinary tract infections. It is also used to help treat severe acne and to treat trachoma (a chronic eye infection) and conjunctivitis (pinkeye). Tetracycline is often an alternative drug for people who are allergic to penicillin.
Enterocycline Pharmacology
Tetracycline is a short-acting antibiotic semisynthetically produced from chlortetracycline, which is derived from Streptomyces aureofaciens. Tetracycline inhibits cell growth by inhibiting translation. It binds to the 30S ribosomal subunit and prevents the amino-acyl tRNA from binding to the A site of the ribosome. This binding is reversible in nature.
Enterocycline Absorption
Bioavailability is less than 40% when administered via intramuscular injection, 100% intravenously, and 60-80% orally (fasting adults). Food and/or milk reduce GI absorption of oral preparations of tetracycline by 50% or more.
Enterocycline side effects and Toxicity
LD50=808mg/kg (orally in mice)
Enterocycline Patient Information
Enterocycline Organisms Affected
Enteric bacteria and other eubacteria
