Purocyclina
Purocyclina Brand names, Purocyclina Analogs
- Abramycin
- Abricycline
- Achromycin
- Achromycin V
- Achromycin, Naphthacene Derivative
- Actisite
- Agromicina
- Ambramicina
- Ambramycin
- Amycin
- Anhydrotetracycline
- Aureomycin
- Bio-Tetra
- Biocycline
- Bristaciclin
- Bristaciclin α
- Bristaciclina
- Bristacycline
- Cefracycline
- Ciclibion
- Copharlan
- Criseociclina
- Cyclomycin
- Cyclopar
- Cytome
- Democracin
- Deschlorobiomycin
- Dumocyclin
- Enterocycline
- Hostacyclin
- Lexacycline
- Limecycline
- Liquamycin
- Medocycline
- Mericycline
- Micycline
- Neocycline
- Oletetrin
- Omegamycin
- Orlycycline
- Oxytetracycline HCl
- Panmycin
- Polycycline
- Polyotic
- Purocyclina
- Resteclin
- Retet
- Robitet
- Roviciclina
- SK-Tetracycline
- Solvocin
- Sumycin
- Sumycin Syrup
- TAC
- TC
- Terramycin
- Tetra-CO
- Tetrabon
- Tetrachel
- Tetracycl
- Tetracycline HCl
- Tetracycline II
- Tetracyn
- Tetradecin
- Tetrafil
- Tetramed
- Tetraverine
- Tetrex
- Topicycline
- Tsiklomistsin
- Tsiklomitsin
- Veracin
- Vetacyclinum
Purocyclina Brand Names Mixture
- Delta-Albaplex tablets (Novobiocin sodium + Prednisolone + Tetracycline hydrochloride)
- Neo Chlor PWR (Neomycin sulfate + Tetracycline hydrochloride)
- Neo-Chlor (Neomycin sulfate + Tetracycline hydrochloride)
- Neotetramed PWR (Neomycin sulfate + Tetracycline hydrochloride)
- P Onytricin P (Calcium D-pantothenate + Menadione sodium bisulfite + Nicotinamide + Tetracycline hydrochloride + Vitamin A + Vitamin B12 + Vitamin B2 + Vitamin B6 + Vitamin D3 + Vitamin E)
Purocyclina Chemical_Formula
C22H24N2O8
Purocyclina RX_link
http://www.rxlist.com/cgi/generic2/tetcycl2.htm
Purocyclina fda sheet
Purocyclina msds (material safety sheet)
Purocyclina Synthesis Reference
J. H. Boothe et al., J. Am. Chem. Soc. 75, 4621 (1953)
Purocyclina Molecular Weight
444.435 g/mol
Purocyclina Melting Point
165oC
Purocyclina H2O Solubility
231 mg/L at 25 oC (SRC PhysProp experimental -- YALKOWSKY,SH & DANNENFELSER,RM (1992))
Purocyclina State
Solid
Purocyclina LogP
-0.304
Purocyclina Dosage Forms
Tablets; Oral suspension; Capsules; Topical solution; Ophthalmic suspension; IV injection; IM injection; Ointment
Purocyclina Indication
Used to treat bacterial infections such as Rocky Mountain spotted fever, typhus fever, and tick fevers; upper respiratory infections; pneumonia; gonorrhea; amoebic infections; and urinary tract infections. It is also used to help treat severe acne and to treat trachoma (a chronic eye infection) and conjunctivitis (pinkeye). Tetracycline is often an alternative drug for people who are allergic to penicillin.
Purocyclina Pharmacology
Tetracycline is a short-acting antibiotic semisynthetically produced from chlortetracycline, which is derived from Streptomyces aureofaciens. Tetracycline inhibits cell growth by inhibiting translation. It binds to the 30S ribosomal subunit and prevents the amino-acyl tRNA from binding to the A site of the ribosome. This binding is reversible in nature.
Purocyclina Absorption
Bioavailability is less than 40% when administered via intramuscular injection, 100% intravenously, and 60-80% orally (fasting adults). Food and/or milk reduce GI absorption of oral preparations of tetracycline by 50% or more.
Purocyclina side effects and Toxicity
LD50=808mg/kg (orally in mice)
Purocyclina Patient Information
Purocyclina Organisms Affected
Enteric bacteria and other eubacteria
